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Oct 1 2023;13(4)doi:10.5826/dpc.1304a255 Razavi M, Jamilian M, Kashan ZF, Heidar Z, Mohseni M, Ghandi Y,

Usual limitations of the studies concerning risk factors for DPN are: predominance of cross-sectional studies, inconsistent diagnostic criteria of DPN, high statistical heterogenity, inadequate assessment of risk factor duration and missclassification of outcomes

Optical properties were examined using photoluminescence (PL) and ultravioletvisible (UVvisible) spectroscopies

However, the fundamental constraint remains: as an agonist of the impaired receptor itself, its mechanism is intrinsically compromised, which may limit efficacy and necessitate robust validation

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The absence of rigorous human trials means safety and efficacy remain unestablished, said Sohaib Imtiaz, MD, a board-certified lifestyle medicine doctor and chief medical officer for the People Inc